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March 24, 2025

How light stabilizes a stress-response protein to help plants survive harsh environments

COP1-ERF1-SCE1 regulatory module fine-tunes stress response under light-dark cycle in Arabidopsis plants. Credit: National Taiwan University
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COP1-ERF1-SCE1 regulatory module fine-tunes stress response under light-dark cycle in Arabidopsis plants. Credit: National Taiwan University

Researchers at National Taiwan University discovered how light stabilizes a key stress-response protein, offering insights into improving crop resilience to harsh environments.

Understanding how respond to environmental stress is crucial for improving crop resilience. Now, in a new study in Plant, Cell & Environment, researchers from National Taiwan University have uncovered how light stabilizes a key stress-response protein, offering new insights into plant adaptation.

The research team investigated ERF1, a transcription factor that helps plants tolerate drought and high salinity. While ERF1 is essential for plant survival under stress, its fluctuates under different . The team discovered that two enzymes鈥擲CE1 and COP1鈥攃ompete to regulate ERF1's stability, directly influencing the plant's ability to withstand .

Under light conditions, SCE1 interacts with ERF1 and modifies it through SUMOylation, preventing its degradation. This allows ERF1 to activate stress-response genes and improve plant resilience. However, in darkness, COP1 modifies ERF1 differently, marking it for degradation and weakening the plant's stress response.

"We were excited to find that these two enzymes compete to determine ERF1's stability," says Hui-Hsien Chang, co-first author of the study. "This competition ultimately influences how well plants respond to ."

By altering ERF1's modification sites, the team demonstrated that ERF1 could be stabilized even in darkness. These findings provide a new approach to engineering stress-tolerant crops by fine-tuning light-responsive pathways.

"Our findings provide a clearer understanding of how plants use light to regulate stress responses," explains Prof. Mei-Chun Cheng, corresponding author of the study. "This knowledge could be applied to developing crops that are better suited to changing climates."

The results of this study could help guide agricultural strategies aimed at developing climate-resilient crops.

More information: Wen鈥怌hi Lin et al, COP1鈥怑RF1鈥怱CE1 regulatory module fine鈥恡unes stress response under light鈥恉ark cycle in Arabidopsis, Plant, Cell & Environment (2024).

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Light stabilizes the stress-response protein ERF1 in plants, enhancing their resilience to drought and high salinity. Under light conditions, the enzyme SCE1 modifies ERF1 through SUMOylation, preventing its degradation and allowing activation of stress-response genes. In darkness, COP1 marks ERF1 for degradation, weakening the stress response. Modifying ERF1's sites can stabilize it even in darkness, offering a strategy for engineering stress-tolerant crops.

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