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Tomato ripening regulated by the same cellular process that slows aging in animals and humans

tomato plant
Credit: Pixabay/CC0 Public Domain

In research in New Phytologist, investigators reveal that tomato ripening is regulated by the same mechanism that contributes to humans' and animals' life- and health spans.

The mechanism, called autophagy, regulates cellular recycling and operates in all lifeforms apart from bacteria. This latest work shows that autophagy affects tomato fruit ripening by controlling the production of ethylene. Ethylene is the primary hormone that controls ripening in many fruits such as apples, bananas, mangoes, avocados, and tomatoes.

To assess the role of autophagy in ripening, the team of researchers from the Volcani Institute, in Israel, and the University of Tübingen, in Germany, generated tomato plants that allow a temporal genetic repression of autophagy, specifically in mature non-ripe fruits.

In these fruits, ethylene production and ripening were initiated prematurely relative to fruits with regular autophagy activity. Therefore, similar to its impact on animals, autophagy delays aging in fruit.

The ability to regulate fruit ripening has important implications for reducing , improving the choice of produce available to consumers, and addressing sustainable food security.

"It is estimated that around 40% of global agricultural produce is lost or wasted, which has significant financial, nutritional, and environmental implications," said corresponding author Simon Michaeli, Ph.D., of the Volcani Institute.

"Eventually, we may exploit knowledge of the cellular and that govern ripening to reduce produce loss and waste in the from farmers to our kitchens. This brings us to our next task: identifying the molecular mechanism by which regulates ethylene onset."

More information: Autophagy Restricts Tomato Fruit Ripening Via a General Role in Ethylene Repression, New Phytologist (2025).

Journal information: New Phytologist

Provided by Wiley

Citation: Tomato ripening regulated by the same cellular process that slows aging in animals and humans (2025, May 7) retrieved 17 August 2025 from /news/2025-05-tomato-ripening-cellular-aging-animals.html
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