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Search results for genome editing

Biotechnology 21 hours ago

Generative AI can outperform nature at designing proteins to edit the genome

Researchers at Integra Therapeutics, in collaboration with the Pompeu Fabra University (UPF) Department of Medicine and Life Sciences (MELIS) and the Center for Genomic Regulation (CRG), have designed and experimentally validated ...

Plants & Animals Sep 30, 2025

Seeing red: An invention is transforming the way scientists track genes

"RUBY"—a cost-effective innovation designed to track gene activity—is proving valuable across a range of fields. It all started with the idea of finding a better way to monitor genes.

Cell & Microbiology Sep 30, 2025

Egg yolk proves key to establishing authentic embryonic stem cells from birds

Egg whites may be perfect for a health-conscious breakfast, but egg yolks turned out to be the key ingredient for cultivating bird embryonic stem cells (ESCs) in the lab. Using a growing medium of egg yolk along with a few ...

Biotechnology Sep 29, 2025

Scientists reveal functional RNA splitting mechanism behind origin of type V CRISPR systems

CRISPR-Cas systems are adaptive immune systems found in prokaryotes that defend against invading nucleic acids through CRISPR RNA-guided cleavage. Type V CRISPR-Cas (Cas12) systems, in particular, serve as one of today's ...

Biotechnology Sep 25, 2025

Bridge recombinases, optimized for human cells, enable massive programmable DNA rearrangements

For decades, gene-editing science has been limited to making small, precise edits to human DNA, akin to correcting typos in the genetic code. Arc Institute researchers are changing that paradigm with a universal gene editing ...

Biotechnology Sep 24, 2025

Screening approach enhances CRISPR genome-editing efficiency

Natural systems such as CRISPR-associated transposons (CASTs) offer a targetable, one-step way to edit genomes. However, adapting them for biomedical applications has been challenging.

Molecular & Computational biology Sep 24, 2025

Gene editing, traditional crossbreeding produce disease-resistant cacao plants

In a development that could help protect one of the world's most beloved agricultural commodities, a research team at Penn State has successfully created disease-resistant cacao plants using gene-editing technology. According ...

Biochemistry Sep 24, 2025

Different types of magic mushrooms use unique biochemical paths to produce the same active compound

A German-Austrian team led by Friedrich Schiller University Jena and Leibniz-HKI has been able to biochemically demonstrate for the first time that different types of mushrooms produce the same mind-altering active substance, ...

Biotechnology Sep 22, 2025

Dual-mode CRISPR system enables simultaneous on and off gene control

Turning genes on and off is like flipping a light switch, controlling whether genes in a cell are active. When a gene is turned on, the production of proteins or other substances is promoted; when it's turned off, production ...

Biotechnology Sep 22, 2025

Compact Cas9d enzyme revealed as promising genome-editing tool

A research team led by Prof. Wang Yanli from the Institute of Biophysics of the Chinese Academy of Sciences has revealed the structure and mechanism of a highly active Type II-D Cas9, offering a promising new tool for genome ...

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