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Search results for CRISPR-Cas9

Bio & Medicine May 22, 2025

Gene delivery system uses nanostraws and electrical pulses to engineer cancer-fighting immune cells

Researchers at the National University of Singapore (NUS) have developed a scalable, non-viral technology that efficiently delivers genetic material into human immune cells. The platform, called Nanostraw Electro-actuated ...

Biotechnology May 21, 2025

Organoid research platform allows investigation of antiviral immunity in bats

Bats are known as natural hosts for highly pathogenic viruses such as MERS- and SARS-related coronaviruses, as well as the Marburg and Nipah viruses. In contrast to the severe and often fatal disease outcomes these viruses ...

Cell & Microbiology May 21, 2025

Mapping ATP's journey: Key protein identified as gateway for energy delivery into endoplasmic reticulum

A team of scientists has answered a long-standing question in cell biology, uncovering how the cell's main energy currency, ATP, is transported into the endoplasmic reticulum (ER). Disrupted energy transport could affect ...

Cell & Microbiology May 16, 2025

Scientists identify new defense mechanism in CRISPR system

Every living creature on Earth needs to protect itself from things that would do it harm. Bacteria are no different. And despite their relative simplicity, they deploy remarkably savvy defensive strategies against viral invaders. ...

Biotechnology May 15, 2025

Advanced gene editor enables more precise insertion of complete genes

Ask scientists which gene-editing tool is most needed to advance gene therapy, and they'd probably describe a system that's now close to realization in the labs of Samuel Sternberg at Columbia University Vagelos College of ...

Biotechnology May 15, 2025

Cas9 ancestor engineered into a compact genome editing tool

Scientists at the McGovern Institute and the Broad Institute of MIT and Harvard have reengineered a compact RNA-guided enzyme they found in bacteria into an efficient, programmable editor of human DNA. The engineered protein, ...

Biotechnology May 8, 2025

The first genetic editing in spiders with CRISPR鈥怌as yields colorful silk

The University of Bayreuth's Biomaterials research group has, for the first time, successfully applied the CRISPR-Cas9 gene-editing tool to spiders. Following the genetic modification, the spiders produced red fluorescent ...

Bio & Medicine Apr 30, 2025

Engineered extracellular vesicles facilitate delivery of advanced medicines

Researchers at Karolinska Institutet have developed a technique that enables efficient delivery of therapeutic proteins and RNA to cells. The method, published in Nature Communications, shows promising results in animal studies ...

Molecular & Computational biology Apr 29, 2025

Computational tool sheds light on DNA regulation in cancer and genome editing

Researchers from the University of Eastern Finland, Aalto University and the University of Oulu have developed a new computational method for exploring DNA sequence patterns. The method, called KMAP, enables intuitive visualization ...

Cell & Microbiology Apr 24, 2025

Scientists repurpose gene editing tool to help uncover hidden microbial diversity

Pioneering research led by the University of Bristol has repurposed a gene-editing tool to help shed light on the true biodiversity present in natural environments. The study, published in the journal Royal Society Open Science, ...

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