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Search results for genome editing

Biotechnology Dec 4, 2024

Serious side effect of using CRISPR-Cas gene scissors uncovered: AZD7648 molecule can destroy parts of genome

Genome editing with various CRISPR-Cas molecule complexes has progressed rapidly in recent years. Hundreds of labs around the world are now working to put these tools to clinical use and are continuously advancing them.

Biotechnology Dec 3, 2024

Customized CRISPR toolkit allows remote-controlled genome editing

Thanks to CRISPR, medical specialists will soon have unprecedented control over how they treat and prevent some of the most challenging genetic disorders and diseases.

Cell & Microbiology Nov 26, 2024

Better health diagnostics through genetically engineered embedded sentinel cells

Cells can now be genetically programmed to record their histories within their genomes, a development that could revolutionize the study of developmental and disease processes, according to a collaborative work by researchers ...

Biotechnology Nov 25, 2024

Researchers create high-resistant starch rice by impaired amylopectin synthesis

Rice is one of the most important staple crops and an excellent starch-provider. Resistant starch (RS) has shown beneficial effects on diabetes, weight management and inflammatory bowel disease.

Molecular & Computational biology Nov 20, 2024

Cas9-PE system achieves precise editing and site-specific random mutation in rice

Achieving the aggregation of different mutation types at multiple genomic loci and generating transgene-free plants in the T0 generation is an important goal in crop breeding. Although prime editing (PE), as the latest precise ...

Biotechnology Nov 14, 2024

New tool allows researchers to study gene mutation directly within living human cells

Gene mutations have consequences both good and bad—from resistance to conditions like diabetes to susceptibility to certain cancers. In order to study these mutations, scientists need to introduce them directly into human ...

Biotechnology Nov 12, 2024

Using CRISPR to decipher whether gene variants lead to cancer

In recent years, scientists have created a range of new methods based on CRISPR-Cas technology for precisely editing the genetic material of living organisms. One application is in cell therapy: A patient's immune cells can ...

Ecology Nov 4, 2024

Deep-sea corals are home to previously unknown bacteria with extremely small genomes, scientists discover

A German-American research team has discovered two highly unusual bacterial species in the tissue of two deep-sea corals from the Gulf of Mexico. These previously unknown coral symbionts have an extremely reduced genome and ...

Cell & Microbiology Oct 31, 2024

The human spliceosome: Decade-long study reveals first blueprint of the most complex molecular machine inside every cell

Researchers at the Center for Genomic Regulation (CRG) in Barcelona have created the first blueprint of the human spliceosome, the most complex and intricate molecular machine inside every cell. The scientific feat, which ...

Plants & Animals Oct 31, 2024

A new piece in the grass pea puzzle: Updated genome sequence published

An international research collaboration has completed the most detailed genome assembly to date of grass pea (Lathyrus sativus).

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