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Search results for drug discovery

Molecular & Computational biology Jun 3, 2025

Mechanical model reveals how prions trigger a domino effect to spread misfolded proteins

Prions, mysterious shape-shifting proteins, can lead to brain disorders such as Creutzfeldt-Jakob disease in humans and bovine spongiform encephalopathy, "mad cow disease" in cattle, yet they can also play essential roles ...

Evolution Jun 3, 2025

MN1 gene study reveals link between brain and skull co-evolution

A new study from the Max Planck Institute for Evolutionary Biology has uncovered how the MN1 gene evolved to shape both the brain and skull during embryogenesis—a link with profound implications for understanding evolution ...

Ecology Jun 2, 2025

Long-awaited mystery fungus sought by LSD's inventor discovered

Making a discovery with the potential for innovative applications in pharmaceutical development, a West Virginia University microbiology student has found a long sought-after fungus that produces effects similar to the semisynthetic ...

Analytical Chemistry Jun 2, 2025

Enhancing molecular machine learning with quantum-chemical insight

Molecular machine learning (ML) underpins critical workflows in drug discovery, material science, and catalyst optimization by rapidly predicting molecular interactions and properties. For instance, in drug discovery, ML ...

Polymers May 30, 2025

Custom-designed polymers open new path to electrochemical separations for sustainable drug manufacturing

Enantiomers, or molecule pairs that are mirror images of each other, make up more than half of FDA-approved drugs in use today, including those used in treatments for cancer, neurologic diseases and arthritis. Separating ...

Biochemistry May 22, 2025

One-pot protein screening accelerates bioscience and drug discovery

Machine learning and supercomputing have brought about a revolution in computational drug discovery. More therapeutic candidates, like antibodies that bind to and fight the SARS-CoV-2 virus, can be explored and simulated ...

Evolution May 21, 2025

Factors behind why some spiders are more venomous than others revealed

A new study by researchers at the University of Galway's School of Natural Sciences has revealed why some spiders possess venom that is far more potent than others.

Cell & Microbiology May 13, 2025

AI can identify genetic perturbations from cell images, offering new path for drug discovery

Researchers at the Paul Scherrer Institute PSI have developed an AI that could open up a new, cost-effective approach to identifying genetic perturbation patterns in cell images—potentially enabling the development of new ...

Biotechnology May 12, 2025

Q&A: AI speeds up search for RNA-targeting drugs, opening new therapeutic possibilities

The majority of RNAs in each of our cells don't code for any of the thousands of proteins that make up our bodies. Instead, noncoding RNAs have critical roles in many biological processes—such as gene expression—making ...

Biochemistry May 6, 2025

Accelerating drug discovery with a single carbon atom

A research team from the University of Oklahoma has pioneered a method that could accelerate drug discovery and reduce pharmaceutical development costs. Their work, published in the Journal of the American Chemical Society, ...

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