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Evolution May 21, 2025

Factors behind why some spiders are more venomous than others revealed

A new study by researchers at the University of Galway's School of Natural Sciences has revealed why some spiders possess venom that is far more potent than others.

Cell & Microbiology May 13, 2025

AI can identify genetic perturbations from cell images, offering new path for drug discovery

Researchers at the Paul Scherrer Institute PSI have developed an AI that could open up a new, cost-effective approach to identifying genetic perturbation patterns in cell images—potentially enabling the development of new ...

Biotechnology May 12, 2025

Q&A: AI speeds up search for RNA-targeting drugs, opening new therapeutic possibilities

The majority of RNAs in each of our cells don't code for any of the thousands of proteins that make up our bodies. Instead, noncoding RNAs have critical roles in many biological processes—such as gene expression—making ...

Biochemistry May 6, 2025

Accelerating drug discovery with a single carbon atom

A research team from the University of Oklahoma has pioneered a method that could accelerate drug discovery and reduce pharmaceutical development costs. Their work, published in the Journal of the American Chemical Society, ...

Cell & Microbiology Apr 28, 2025

Fungi dwelling on human skin may provide new antibiotics

University of Oregon researchers have uncovered a molecule produced by yeast living on human skin that showed potent antimicrobial properties against a pathogen responsible for a half-million hospitalizations annually in ...

Biochemistry Apr 23, 2025

Efficient selection platform enables discovery of novel lysine-targeting covalent inhibitors

In a study published in Angewandte Chemie International Edition, a research team integrated activity-based protein profiling (ABPP) data with the covalent DNA-encoded chemical library (CoDEL) technology and identified structurally ...

Biochemistry Apr 17, 2025

Free tool streamlines ALS drug discovery with mass-spectrometry based model

Interested in finding a better way to develop drugs to treat amyotrophic lateral sclerosis (ALS), Northeastern researcher Jeffrey Agar and a team of scientists came up with a technique that improves the drug discovery workflow ...

Cell & Microbiology Apr 17, 2025

Scientists hack cell entry to supercharge cancer drugs

A new discovery could pave the way for more effective cancer treatment by helping certain drugs work better inside the body. Scientists at Duke University School of Medicine, University of Texas Health Science Center at San ...

Analytical Chemistry Apr 16, 2025

AI enhances molecular design with uncertainty quantification

In a major step toward more reliable AI-assisted molecular design, researchers from National Taiwan University have demonstrated that incorporating uncertainty quantification (UQ) into graph neural network (GNN) models significantly ...

Biochemistry Apr 15, 2025

Researchers resurrect extinct gene in plants with major implications for drug development

Northeastern University researchers resurrected an extinct plant gene, turning back the evolutionary clock to pave a path forward for the development and discovery of new drugs.

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