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Search results for stem cells

Cell & Microbiology Sep 19, 2023

Scientists show how the signaling molecules BMP and FGF guide cell differentiation during embryonic development

Bricklayer, banker, teacher—choosing a career is one of the most exciting and important decisions in our lives. At the beginning of embryonic development, our cells are also faced with this decision. Some of them become ...

Cell & Microbiology Sep 8, 2023

Inheritance of parental histones safeguards fate of mouse embryonic stem cells

Researchers led by Prof. Gan Haiyun from the Shenzhen Institute of Advanced Technology (SIAT) of the Chinese Academy of Sciences (CAS) have documented the parental histones inheritance safeguard mechanism, in which parental ...

Cell & Microbiology Sep 7, 2023

Researchers grow embryonic humanized kidneys inside pigs for 28 days

Guangzhou Institutes of Biomedicine and Health researchers have successfully created chimeric embryos containing a combination of human and pig cells. When transferred into surrogate pig mothers, the developing humanized ...

Cell & Microbiology Sep 6, 2023

Human embryo models grown from stem cells

A research team headed by Prof. Jacob Hanna at the Weizmann Institute of Science has created complete models of human embryos from stem cells cultured in the lab—and managed to grow them outside the womb up to day 14. As ...

Cell & Microbiology Aug 28, 2023

Enhancing the immunosuppressive capacity of human-umbilical-cord–derived mesenchymal stem cells

The immunosuppressive capacity of mesenchymal stem cells (MSCs) is dependent on the "license" of several proinflammatory factors to express immunosuppressive factors such as programmed cell death 1 ligand 1 (PD-L1), which ...

Cell & Microbiology Aug 28, 2023

Constitutive aryl hydrocarbon receptor facilitates regenerative potential of mouse bone marrow mesenchymal stromal cells

Bone marrow mesenchymal stromal cells (BMSCs) are the commonly used seed cells in tissue engineering. Aryl hydrocarbon receptor (AhR) is a transcription factor involved in various cellular processes. However, the function ...

Cell & Microbiology Aug 28, 2023

Quercetin ameliorates oxidative stress-induced senescence in rat nucleus pulposus-derived mesenchymal stem cells: Study

Intervertebral disk degeneration (IDD) is a main contributor to low back pain. Oxidative stress, which is highly associated with the progression of IDD, increases senescence of nucleus pulposus-derived mesenchymal stem cells ...

Cell & Microbiology Aug 22, 2023

Discovery of how stem cell niche guides differentiation into functional cells is a significant step towards therapies

Researchers at the Hong Kong University of Science and Technology (HKUST) have found how stem cells' surrounding environment controls them to differentiate into functional cells, a breakthrough critical for using stem cells ...

Cell & Microbiology Aug 18, 2023

Researchers discover how stem cells choose their identity

AMOLF researchers discovered that stem cells first specialize into a functional cell and then move to their proper location—rather than the other way around.

Cell & Microbiology Aug 16, 2023

Scientists find way to wipe a cell's memory to better reprogram it as a stem cell

In a study published in Nature, Australian scientists have resolved a long-standing problem in regenerative medicine. Led by Professor Ryan Lister from the Harry Perkins Institute of Medical Research and The University of ...

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