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Search results for therapeutic protein

Molecular & Computational biology Dec 5, 2024

Protein engineering research reveals the mysteries of life, enabling advances in pharmaceuticals

Proteins are so much more than nutrients in food. Virtually every reaction in the body that makes life possible involves this large group of molecules. And when things go wrong in our health, proteins are usually part of ...

Cell & Microbiology Dec 4, 2024

Discovery of molecular switch explains how bacteria control their protein biosynthesis through cell metabolism

Protein biosynthesis—the process whereby cells produce protein molecules, which are essential for life and growth—is a highly complex and strictly regulated affair. An interdisciplinary team led by LMU biologist PD Dr. ...

Molecular & Computational biology Dec 4, 2024

AI model enables reliable and accurate protein-ligand complex prediction

Understanding protein–ligand interactions is fundamental to molecular biology and biochemistry. These interactions are at the heart of many cellular processes, from enzyme catalysis to signal transduction. The foundational ...

Cell & Microbiology Dec 2, 2024

Scientists develop self-sustained protein transport and tissue assembly in artificial cells

In a new Nature Communications study, scientists have developed a novel method for artificial cells to interact with their external environment without the need for complex modification processes.

Cell & Microbiology Nov 22, 2024

New technique points to unexpected uses for snoRNA across many cell types

Dynamic, reversible modifications of DNA and RNA regulate how genes are expressed and transcribed, which can influence cellular processes, disease development, and overall organismal health. Small nucleolar RNAs (snoRNAs) ...

Cell & Microbiology Nov 14, 2024

Slow editing of protein blueprints leads to cell death, spliceosome study discovers

An international research team has uncovered a new mechanism crucial to the production of cellular proteins. When this mechanism is disrupted, the blueprints used by the cell to produce proteins are inaccurately edited through ...

Bio & Medicine Nov 14, 2024

Scientists engineer stable protein complexes for targeted cancer therapies

Researchers from Auburn University, partnering with the University of Basel in Switzerland, have discovered a new way to make a cancer-targeting protein complex more stable, opening doors to better cancer treatments. Led ...

Biochemistry Nov 14, 2024

Using genetic code expansion to study membrane proteins

Over the years, chemical biology methods have made an important contribution to the study of integral membrane proteins. A key modern approach is genetic code expansion (GCE), which makes it possible to modify proteins directly ...

Biochemistry Oct 29, 2024

Scientists outline a roadmap for creating 'Trojan horse' peptides that cross biological barriers

A new review of the research on cell-penetrating peptide (CPP) clusters by scientists from Macquarie University and Oxford University will provide a roadmap for biomedical scientists to develop the next generation of treatments ...

Molecular & Computational biology Oct 28, 2024

Team develops deep learning model to predict protein conformational changes

Recently, a research team has collaborated to propose a deep learning model for predicting protein conformational changes. This achievement has been published online in Advanced Science.

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