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Search results for therapeutic protein

Biochemistry Feb 14, 2024

Discovery of new plant protein fold may be seed for anti-cancer drugs

University of Michigan researchers are celebrating their discovery of a new plant biochemistry and its unusual ability to form cyclic peptides—molecules that hold promise in pharmaceuticals as they can bind to challenging ...

Cell & Microbiology Feb 6, 2024

RNA splicing regulation discovery provides insight into bone diseases

In today's aging societies, bone and joint diseases are becoming increasingly common. For example, in Japan alone, over 12 million people suffer from osteoporosis, a condition that severely weakens bones and makes them fragile. ...

Molecular & Computational biology Feb 5, 2024

Researchers uncover the architecture of poxvirus cores

A recent re-emergence and outbreak of mpox brought poxviruses back as a public health threat, underlining an important knowledge gap at their core. Now, a team of researchers from the Institute of Science and Technology Austria ...

Biotechnology Jan 29, 2024

New AI model designs proteins to deliver gene therapy

Researchers at the University of Toronto have used an artificial intelligence framework to redesign a crucial protein involved in the delivery of gene therapy.

Biochemistry Jan 29, 2024

Molecular simulation AI tool reveals unresolved structure of transporter protein

In a groundbreaking study, researchers have unveiled a previously unknown conformational state of a crucial transporter protein, OxlT, which plays a vital role in preventing kidney stone formation. This discovery, achieved ...

Biochemistry Jan 25, 2024

New simulation tool advances molecular modeling of biomolecular condensates

A University of Massachusetts Amherst team has made a major advance toward modeling and understanding how intrinsically disordered proteins (IDPs) undergo spontaneous phase separation, an important mechanism of subcellular ...

Cell & Microbiology Jan 22, 2024

Scientists make COVID receptor protein in mouse cells

A team of scientists at the U.S. Department of Energy's (DOE) Brookhaven National Laboratory and Columbia University has demonstrated a way to produce large quantities of the receptor that SARS-CoV-2, the virus that causes ...

Biotechnology Jan 16, 2024

Manipulating polyamines to enhance antibody efficacy: A novel approach in biotechnology

Monoclonal antibodies (mAbs) are laboratory-designed proteins that mimic the immune system's antibodies. To date, many therapeutic mAbs belonging to the immunoglobulin G (IgG) class of antibodies, have been approved for the ...

Molecular & Computational biology Jan 11, 2024

Researchers discover protein complex that controls DNA repair

The repair of damage to genetic material (DNA) in the human body is carried out by highly efficient mechanisms that have not yet been fully researched. A scientific team led by Christian Seiser from MedUni Vienna's Center ...

Cell & Microbiology Jan 4, 2024

Unlocking the secrets of disease-causing fungus Aspergillus fumigatus

An international team of researchers, led by Professor Gustavo Goldman of the University of São Paulo and Maynooth University's Dr. Özgür Bayram, has unveiled ground-breaking findings on Aspergillus fumigatus, which can ...

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