Identifying new ways to target proteins involved in human diseases is a priority for many researchers around the world. However, discovering how to alter the function of these proteins can be difficult, especially in live ...
Just like a doctor adjusts the dose of a medication to the patient's needs, the expression of therapeutic genes, those modified in a person to treat or cure a disease via gene therapy, also needs to be maintained within a ...
When it comes to delivering drugs to the body, a major challenge is ensuring that they remain in the area they're treating and continuing to deliver their payload accurately. While major strides have been made in delivering ...
The membrane that encases a biological cell is not simply a barrier; it is chock full of proteins involved in all sorts of critical biological functions. To really understand what membrane proteins are doing and how, researchers ...
Proteins are building blocks of our bodies, but they do not work solo. They form partners to facilitate in different biological processes that keep us going. However, analyzing how proteins interact at a molecular level can ...
Scientists have identified the protein that helps poison dart frogs safely accumulate their namesake toxins, according to a study published today in eLife. The findings solve a long-standing scientific mystery and may suggest ...
A new technology co-developed at EMBL Hamburg provides new insights into mRNA pharmaceuticals and other nanomedicines, which can be helpful for the development of new products
A multidisciplinary study published in Nature has elucidated the structure of the machinery responsible for writing much of our "dark genome"—the 98% of our DNA that has largely unknown biological function. These results ...
Today, medicines based on antibodies—proteins that fight infection and disease—are prescribed for everything from cancer to COVID-19 to high cholesterol. The antibody drugs are supplied by genetically-engineered cells ...
Most diseases are caused by proteins that have spun out of control. Unfortunately, so far, conventional drugs have been able to stop only a fraction of these troublemakers. A new class of drugs known as PROTACs holds great ...
