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Biotechnology Jul 28, 2023

Researchers develop method to predict gene expression across different tissues and cell types

In recent years, a virtual tidal wave of studies linking the expression of certain genes to complex diseases as varied as cancer and diabetes has raised hopes for major advances in medical treatment and drug discovery.

Analytical Chemistry Jul 19, 2023

Scientists develop revolutionary new approach to designing catalysts for chemical reactions

Chemists at King's College London have made a breakthrough in the way they develop artificial helix shapes for the amino acids that constitute proteins. These new synthetic shapes have the potential to transform processes ...

Bio & Medicine Jul 17, 2023

Researchers craft 'origami DNA' to control virus assembly

Griffith University researchers have played a key role in using DNA "origami" templates to control the way viruses are assembled.

Biotechnology Jul 13, 2023

Researchers demonstrate the power of quantum computing in drug design

Gero, an AI-driven biotech focused on aging and longevity, has demonstrated the feasibility of applying quantum computing for drug design and generative chemistry, which now offers significant promise for the future of healthcare. ...

Biochemistry Jul 13, 2023

Catalyst's ability to mimic liver enzyme could broaden scope of pharmaceutical drug discovery

When a human consumes a pharmaceutical drug, enzymes in the liver break down the substance into metabolites that are water soluble, so the body can more easily excrete them. In some cases, the resulting metabolites may have ...

Cell & Microbiology Jul 7, 2023

Developing a human malaria-on-a-chip disease model

In a new report published on Scientific Reports, Michael J. Rupar, and a research team at Hesperos Inc., Florida, U.S., developed a functional, multi-organ, serum-free system to culture P. falciparum—a protozoan that predominantly ...

Cell & Microbiology Jul 5, 2023

Team develops new drug discovery platform

A highly versatile family of receptors found on the surface of our cells plays a massive role in the multibillion-dollar field of drug discovery. Called G protein-coupled receptors, or GPCRs, they also facilitate a staggering ...

Biochemistry Jun 28, 2023

Novel computational approach reveals previously inaccessible druggable pockets

A team of researchers from the Universities of Amsterdam and Zurich together with the Swiss company Allocyte Pharmaceuticals have for the first time been able to discover allosteric sites in a type of cell surface receptor ...

Biochemistry Jun 28, 2023

The potential of generative AI to accelerate antiviral development and drug discovery

In a new study, researchers from IBM, Oxford University and Diamond Light Source show that IBM's AI Model, MoLFormer, can generate antiviral molecules for multiple target virus proteins, including SARS-CoV-2, that can accelerate ...

Analytical Chemistry Jun 26, 2023

Towards synthesis of phenanthridine-based pharmaceutical compounds

Phenanthridines are heterocyclic compounds consisting of two six-membered benzene rings fused to a six-membered ring containing nitrogen. They are found in many naturally occurring organic compounds known for their anticancer ...

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