Molecular & Computational biology
Jun 19, 2023
Scientists use supercomputer to detail HIV protein mechanism crucial for drug development
Every disease has a protein basis.
See also stories tagged with Drug discovery
Search results for drug discovery
Analytical Chemistry
Jun 19, 2023
Resolving hydrogen atoms in small organic molecules depending on chemical bond type
Extremely intense X-ray pulses can determine the positions of some hydrogen atoms in organic molecules that form small crystals, an all-RIKEN team has shown. Many areas, including drug discovery and materials research, stand ...
Condensed Matter
Jun 16, 2023
Examining 'glitches in the matrix': Team finds ways to harness quantum power of atomic flaws
The most interesting parts of nature are often the imperfections. That's especially true in quantum physics, the atomic-level world where tiny flaws can make a big difference in the ways particles behave and interact.
Molecular & Computational biology
Jun 8, 2023
New model offers a way to speed up drug discovery
Huge libraries of drug compounds may hold potential treatments for a variety of diseases, such as cancer or heart disease. Ideally, scientists would like to experimentally test each of these compounds against all possible ...
Biochemistry
Jun 8, 2023
Mass spectrometry uncovers actions of protein 'glues'
A screening technique commonly used in drug discovery can yield important details about the actions of molecular 'glues' in protein interactions.
Quantum Â鶹ÒùÔºics
Jun 8, 2023
How Schrödinger's cat makes better qubits
Quantum computing uses the principles of quantum mechanics to encode and elaborate data, meaning that it could one day solve computational problems that are intractable with current computers. While the latter work with bits, ...
Molecular & Computational biology
Jun 8, 2023
Scientists reveal regulation mechanism of soybean cyst nematode responses to chemical signals
Soybean cyst nematode (SCN, Heterodera glycines Ichinohe), is a devastating pathogen in soybean. The infective juveniles of nematodes can use phytochemical signals (semiochemicals) released into the rhizosphere as important ...
Cell & Microbiology
Jun 6, 2023
Researchers visualize communication of G protein-coupled receptors, paving way for new drug discovery
A group of researchers led by Prof. Arun K. Shukla in the Department of Biological Sciences and Bioengineering at the Indian Institute of Technology Kanpur (IIT-K) has unraveled a previously unknown mechanism that regulates ...
Analytical Chemistry
May 31, 2023
Crossing the ring: New method enables C-H activation across saturated carbocycles
A new "molecular editing" technique from Scripps Research enables chemists to add new elements to organic molecules at locations that were previously out of reach.
Analytical Chemistry
May 30, 2023
Using AI to create better, more potent medicines
While it can take years for the pharmaceutical industry to create medicines capable of treating or curing human disease, a new study suggests that using generative artificial intelligence could vastly accelerate the drug-development ...
