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Molecular & Computational biology Jun 8, 2023

Scientists reveal regulation mechanism of soybean cyst nematode responses to chemical signals

Soybean cyst nematode (SCN, Heterodera glycines Ichinohe), is a devastating pathogen in soybean. The infective juveniles of nematodes can use phytochemical signals (semiochemicals) released into the rhizosphere as important ...

Cell & Microbiology Jun 6, 2023

Researchers visualize communication of G protein-coupled receptors, paving way for new drug discovery

A group of researchers led by Prof. Arun K. Shukla in the Department of Biological Sciences and Bioengineering at the Indian Institute of Technology Kanpur (IIT-K) has unraveled a previously unknown mechanism that regulates ...

Analytical Chemistry May 31, 2023

Crossing the ring: New method enables C-H activation across saturated carbocycles

A new "molecular editing" technique from Scripps Research enables chemists to add new elements to organic molecules at locations that were previously out of reach.

Analytical Chemistry May 30, 2023

Using AI to create better, more potent medicines

While it can take years for the pharmaceutical industry to create medicines capable of treating or curing human disease, a new study suggests that using generative artificial intelligence could vastly accelerate the drug-development ...

Biochemistry May 30, 2023

Study unlocks key information on major drug target for psychiatric and cognitive disorders, including schizophrenia

An international study led by Monash University has, for the first time, harnessed cutting-edge technology to reveal new and unprecedented information of how a special class of drugs, known as "allosteric modulators" work ...

Biochemistry May 30, 2023

Scientists develop probe that could unlock the mysteries of a vital cellular messenger and lead to new drug discoveries

A study by Loughborough University and the University of Oxford has led to the development of a small molecule probe that could deepen our understanding of a crucial cellular messenger and lead to the development of new therapeutic ...

Biochemistry May 25, 2023

Scientists use AI to find promising new antibiotic to fight evasive hospital superbug

Scientists at McMaster University and the Massachusetts Institute of Technology have used artificial intelligence to discover a new antibiotic that could be used to fight a deadly, drug-resistant pathogen that strikes vulnerable ...

Analytical Chemistry May 22, 2023

Researchers review AI advantages in drug research and development

Scientists have long been challenged by the complex process of drug discovery and development, with investments that often go unrewarded. However, with the advancement of experimental technology and computer hardware, artificial ...

Analytical Chemistry May 19, 2023

Study combines quantum computing and generative AI for drug discovery

Insilico Medicine, a clinical stage generative artificial intelligence (AI)-driven drug discovery company, today announced that it combined two rapidly developing technologies, quantum computing and generative AI, to explore ...

Biochemistry May 18, 2023

Finger on the pulse of drug delivery: Preclinical study could pave the way for multiple drug doses in a single injection

Pharmaceutical drugs can save lives, but taking these medications as prescribed—especially among those with chronic conditions—can be challenging, for a variety of different reasons. Improving medication adherence could ...

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