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Search results for therapeutic protein

Cell & Microbiology Jul 14, 2023

Study discovers novel region for BRD4 transcription and potential therapeutic target

A team of investigators in the laboratory of Ali Shilatifard, Ph.D., the Robert Francis Furchgott Professor and chair of Biochemistry and Molecular Genetics, have discovered a novel protein region responsible for regulating ...

Cell & Microbiology Jul 13, 2023

New research on phage φX174 sheds light on escape mechanism

In the age of COVID-19, the word "virus" stirs up thoughts of contagion, sickness, and even death. But what if there were a virus—a very tiny virus capable of replicating itself hundreds of times every half hour—that ...

Biotechnology Jul 13, 2023

Development of new p38 protein inhibitors with therapeutic potential for some heart diseases

The p38 protein regulates a wide variety of cellular functions and is related to diseases such as chronic inflammation, immunological disorders, or cancer. To date, it has been difficult to find p38 inhibitors for use in ...

Biochemistry Jul 10, 2023

Newly-identified compound inhibits SARS-CoV-2 by targeting the nucleocapsid protein

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread globally since 2020. The nucleocapsid (N) protein plays a crucial role in the life cycle of SARS-CoV-2.

Biotechnology Jul 5, 2023

Scientists engineer living DNA sensors

Early detection of infectious diseases can be key to successful treatment, but we often don't know we are infected until symptoms appear. What if our bodies could detect the presence of an infectious pathogen before the onset ...

Cell & Microbiology Jul 5, 2023

It takes three to tango: Study reveals transcription factors bind DNA, protein and RNA

Transcription factors could be the Swiss Army knives of gene regulation; they are versatile proteins containing multiple specialized regions. On one end they have a region that can bind to DNA. On the other end they have ...

Cell & Microbiology Jun 29, 2023

Researchers remove protein aggregates from cells

Protein aggregates accumulate during aging and are linked to neurodegenerative diseases like Alzheimer's, Parkinson's or Huntington's disease. A new study by the Nyström lab at Gothenburg University, in collaboration with ...

Biotechnology Jun 27, 2023

Researchers develop new base editing tools using AI-predicted protein structure clustering

Gao Caixia's group from the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences has pioneered the use of artificial intelligence (AI)-assisted methods to discover novel deaminase proteins with ...

Cell & Microbiology Jun 15, 2023

Researchers identify a protein as a potential therapeutic target for age-related diseases

A research team from the Hong Kong University of Science and Technology (HKUST) has identified a key protein that may shed light on how to reverse the aging process using the adult stem cell of skeletal muscle (or muscle ...

Molecular & Computational biology Jun 8, 2023

New model offers a way to speed up drug discovery

Huge libraries of drug compounds may hold potential treatments for a variety of diseases, such as cancer or heart disease. Ideally, scientists would like to experimentally test each of these compounds against all possible ...

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