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Search results for CRISPR-Cas9

Biotechnology Dec 3, 2024

Customized CRISPR toolkit allows remote-controlled genome editing

Thanks to CRISPR, medical specialists will soon have unprecedented control over how they treat and prevent some of the most challenging genetic disorders and diseases.

Cell & Microbiology Nov 16, 2024

Selenoproteins open new strategies for treating certain cancers in children

Selenoproteins are crucial for several biological functions, including the breakdown of harmful substances, immune system support, and regulating metabolic processes. However, in specific contexts, these proteins can be misused ...

Biotechnology Nov 14, 2024

New tool allows researchers to study gene mutation directly within living human cells

Gene mutations have consequences both good and bad—from resistance to conditions like diabetes to susceptibility to certain cancers. In order to study these mutations, scientists need to introduce them directly into human ...

Biotechnology Nov 7, 2024

Plant engineering method promises to dramatically improve biofuel and bioproduct development

The ability to genetically engineer plants is largely thanks to a microscopic helper: a bacterium called Agrobacterium tumefaciens. Agrobacterium in the wild causes damaging tumors in flowering plants, including some economically ...

Biotechnology Nov 7, 2024

RNA-targeting CRISPR reveals that hundreds of noncoding RNAs are essential—not 'junk'

Genes contain instructions for making proteins, and a central dogma of biology is that this information flows from DNA to RNA to proteins. But only two percent of the human genome actually encodes proteins; the function of ...

Ecology Nov 5, 2024

Deaf male mosquitoes don't mate, researchers discover

Romance is a complex affair in humans. There's personality, appearance, seduction, all manner of physical and social cues. Mosquitoes are much more blunt. Mating occurs for a few seconds in midair. And all it takes to woo ...

Cell & Microbiology Nov 4, 2024

Newly described anti-viral defense system in bacteria aborts infection by chemically altering mRNA

Like humans and other complex multicellular organisms, single-celled bacteria can fall ill and fight off viral infections. A bacterial virus is caused by a bacteriophage, or, more simply, phage, which is one of the most ubiquitous ...

Ecology Nov 1, 2024

Honeybee gene specifies collective behavior, research shows

Researchers at Heinrich Heine University Düsseldorf (HHU) are collaborating with colleagues from Frankfurt/Main, Oxford and Würzburg to investigate how the complex, cooperative behavior of honeybees (Apis mellifera) is ...

Cell & Microbiology Oct 28, 2024

CRISPR-Cas10 can flood virally infected bacteria with toxic molecules, researchers discover

CRISPR-Cas9 has long been likened to a kind of genetic scissors, thanks to its ability to snip out any desired section of DNA with elegant precision.

Biotechnology Oct 28, 2024

Researchers discover underlying mechanisms that make CRISPR an effective gene editing tool

CRISPR/Cas9 is a gene editing tool that has revolutionized biomedical research and led to the first FDA-approved CRISPR-based gene therapy. However, until now, the precise mechanism of exactly how this tool works and avoids ...

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