Gram-negative bacteria pose a significant threat to global health due to their high resistance to antibiotics compared to that of Gram-positive bacteria. Their formidable defensive capabilities stem from their outer membrane ...
Researchers have developed a simple yet highly effective method for delivering mRNA to target cells, opening up new possibilities for future non-vaccine mRNA medicines for a broad range of diseases.
A University of Queensland-led study has found Australian skinks have evolved molecular armor to stop snake venom from shutting down their muscles. The research has been published in the International Journal of Molecular ...
A new study from researchers at the Advanced Science Research Center at the CUNY Graduate Center (CUNY ASRC) reveals that extremely simple peptides can mimic a biological process that protects sensitive proteins from environmental ...
Proteins sustain life as we know it, serving many important structural and functional roles throughout the body. But these large molecules have cast a long shadow over a smaller subclass of proteins called microproteins.
Leishmaniasis is a parasitic disease that affects up to 1 million people worldwide each year. It is caused by the protozoan Leishmania, transmitted through the bite of a sandfly. Once inside its host—human or animal—the ...
Recent advances in computational protein design have depended mainly on neural networks and machine learning to generate binders. However, the complexity of protein–protein interactions and the limitations of data-driven ...
A KAIST research team led by Professor Won Do Heo (Department of Biological Sciences) has developed an optogenetic platform, RELISR (REversible LIght-induced Store and Release), that enables precise spatiotemporal control ...
Researchers at Harvard Medical School and Brigham and Women's Hospital designed an ingestible capsule that delivers liquid mRNA to the intestines, producing gene expression and reducing inflammation in rats.
A new artificial intelligence model can improve the process of drug and vaccine discovery by predicting how efficiently specific mRNA sequences will produce proteins, both generally and in various cell types.
