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Biochemistry Jun 26, 2025

From brewery to pharma: Brewer's yeast engineered to produce therapeutic peptides

Scientists have developed an innovative method to produce and rapidly analyze a vast array of macrocyclic peptides, molecules increasingly used in modern medicine. The research, published in Nature Communications, harnesses ...

Cell & Microbiology Jun 25, 2025

Iron tug-of-war: How a fungus builds its fortress against the immune system

A study led by a global research consortium offers new hope for patients with mycetoma, a neglected tropical disease. Researchers using an insect model and transcriptome analysis have unraveled the mechanism of iron regulation ...

Quantum Âé¶¹ÒùÔºics Jun 25, 2025

New hybrid quantum–classical computing approach used to study chemical systems

Caltech professor of chemistry Sandeep Sharma and colleagues from IBM and the RIKEN Center for Computational Science in Japan are giving us a glimpse of the future of computing. The team has used quantum computing in combination ...

Cell & Microbiology Jun 24, 2025

Researchers discover how caffeine could slow cellular aging

A new study from the Cellular Aging and Senescence laboratory at Queen Mary University of London's Centre for Molecular Cell Biology reveals how caffeine—the world's most popular neuroactive compound—might do more than ...

Cell & Microbiology Jun 24, 2025

Cryo-EM structures reveal how the reproductive hormone GnRH activates its receptor

In 1977, the Nobel Prize in Âé¶¹ÒùÔºiology or Medicine was awarded to Roger Guillemin and Andrew Schally for their discovery and synthesis of gonadotropin-releasing hormone (GnRH), a key regulator of reproductive function. Today, ...

Cell & Microbiology Jun 23, 2025

Q&A: How parasites—and a bit of serendipity—led to a powerful new drug discovery tool

From cancer to infectious diseases to neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease, there is an undeniable need for new treatments and medications.

Biochemistry Jun 23, 2025

Glowing biosensor streamlines high-throughput drug screening

Drug discovery can be a long and complex process. Medicines for neurodegenerative diseases like Alzheimer's disease are among the most expensive to develop, as animal model results have not proven to be predictive of efficacy ...

Biochemistry Jun 23, 2025

Engineers turn toxic ancient tomb fungus into anti-cancer drug

Penn-led researchers have turned a deadly fungus into a potent cancer-fighting compound. After isolating a new class of molecules from Aspergillus flavus, a toxic crop fungus linked to deaths in the excavations of ancient ...

Bio & Medicine Jun 19, 2025

Nanobody-based 3D immunohistochemistry allows rapid visualization in thick tissue samples

Three-dimensional immunohistochemistry (3D-IHC) has transformed our ability to visualize the spatial arrangement of cells and molecules in intact tissues. However, traditional methods are often time-consuming and suffer from ...

Molecular & Computational biology Jun 18, 2025

Atomic-level mapping of receptor protein reveals potential drug targets for diabetes and obesity

Scientists have unlocked new details on important receptor proteins—promising targets for the creation of novel drugs for metabolic conditions ranging from diabetes to obesity and inflammatory disorders.

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