Researchers find 12 compounds that inhibit tuberculosis bacterium's energy source
A new study by University of Bath scientists has highlighted two new potential families of drug molecules that could open the door to new treatments for tuberculosis.
See also stories tagged with Drug discovery
A new study by University of Bath scientists has highlighted two new potential families of drug molecules that could open the door to new treatments for tuberculosis.
For the first time, chemists have discovered a unique way to control and modify a type of compound widely used in medicines, including a drug used to treat breast cancer.
Researchers in Korea have developed an artificial intelligence (AI) technology that predicts molecular properties by learning electron-level information without requiring costly quantum mechanical calculations. The research ...
Researchers from the National University of Singapore (NUS) have solved a 60-year-old mystery in bacterial cell envelope biology, defining the primary function of an important protein complex responsible for maintaining the ...
A study published in mBio details the vulnerability of coronaviruses to inhibitors of a small protein domain called Mac1, or the "macrodomain," found in all coronaviruses such as SARS-CoV-2 and MERS-CoV.
Proteins have specific biological functions in cells through conformational changes and interactions. Therefore, precise, in situ analysis of protein complex changes is essential for understanding cellular functions, uncovering ...
Imagine that you want to know the plot of a movie, but you only have access to either the visuals or the sound. With visuals alone, you'll miss all the dialog. With sound alone, you will miss the action. Understanding our ...
Scientists have created tiny disk-shaped particles that can swim on their own when hit with light, akin to microscopic robots that move through a special liquid without any external motors or propellers.
Porcine reproductive and respiratory syndrome virus (PRRSV) continues to devastate the global swine industry, yet the structural basis of how small molecules block its entry into host cells remains unclear. Researchers at ...
Every protein in the body is encased in a water shell that directs protein structure, provides vital stability and steers function. Because of this, water molecules represent a powerful but largely underappreciated foothold ...