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Imaging the invisible: Advanced tech targets microplastics in living organisms

Imaging the invisible: advanced tech targets microplastics in living organisms
Diagram illustrating the mass spectrometry imaging process using MALDI and SIMS techniques combined with TOF and Orbitrap analyzers for in situ identification and quantification of microplastics within biological tissues. Credit: Eco-Environment & Health (2024). DOI: 10.1016/j.eehl.2024.05.007

Plastic pollution, particularly the presence of microplastics in living organisms, poses a growing threat to ecosystems and human health. A recent study introduces mass spectrometry imaging (MSI) as a cutting-edge method for detecting and quantifying microplastics in biological samples, offering critical insights into their distribution and potential impacts.

Microplastics, pervasive in both terrestrial and , have been found in diverse organisms, from fish and plants to humans. Traditional imaging techniques, such as fluorescence and , struggle to specifically identify microplastics without extensive sample preparation or artificial labeling, which can introduce errors. These limitations highlight the urgent need for advanced detection methods that can analyze microplastics in their natural state within biological tissues.

This , led by researchers from Nankai University and the University of Massachusetts, and published in Eco-Environment & Health on June 6, 2024, unveils a novel mass spectrometry imaging (MSI) approach that combines matrix-assisted laser desorption/ionization (MALDI) with time-of-flight (TOF) or Orbitrap mass analyzers. This technology enables precise in situ imaging of microplastics in , offering high-resolution spatial analysis of their chemical compositions without the need for labeling.

The new MSI technique overcomes the challenges of traditional methods by allowing direct ionization and analysis of plastic macromolecules within living tissues. By integrating MALDI with TOF or Orbitrap analyzers, the method provides detailed spatial distribution maps and chemical data on microplastics in situ.

This approach preserves the integrity of biological samples, enabling accurate visualization and quantification of microplastics. The study showcases this technology's ability to reveal critical information about the accumulation, movement, and transformation of microplastics in living organisms, shedding light on their potential health and .

Senior researcher Dr. Lei Wang highlighted the study's significance, saying, "This approach offers unprecedented insights into the dynamics of microplastics within biological systems. By precisely mapping and quantifying microplastics in situ, we can better understand their risks to organisms and ecosystems, opening new avenues for research into the health and environmental implications of plastic pollution."

This advanced imaging technique holds immense promise for environmental and health applications. It can provide crucial data on the impact of microplastics on various species, including humans, through high-resolution, non-destructive imaging of their distribution within tissues. This capability may enhance regulatory frameworks and pollution mitigation efforts, supporting the protection of public health and ecosystems.

More information: Ye Li et al, In situ imaging of microplastics in living organisms based on mass spectrometry technology, Eco-Environment & Health (2024).

Provided by Nanjing Institute of Environmental Sciences, MEE

Citation: Imaging the invisible: Advanced tech targets microplastics in living organisms (2024, October 28) retrieved 11 May 2025 from /news/2024-10-imaging-invisible-advanced-tech-microplastics.html
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