麻豆淫院

Wheat has a very large and complex genome. Researchers have found that different varieties can use their genes in different ways. By studying RNA鈥攖he molecules that carry out instructions from DNA鈥攔esearchers can see which genes are active and when. By mapping this gene activity for the first time, researchers are able to accelerate international wheat breeding programs, developing new varieties of wheat which can adapt to the rapidly escalating climate emergency.

The research is published in Nature Communications.

Wheat is the most widely cultivated crop in the world, with over 215 million hectares grown annually. To meet the demands of a growing global population, plant breeders face the challenge of increasing wheat production by an estimated 60% within the next 40 years.

The wheat pan-transcriptome offers a powerful tool to help meet this challenge. It will enable plant breeders to accelerate yield improvements and develop more resilient wheat varieties鈥攂etter equipped to cope with rising temperatures, water shortages, and poor soil quality. Importantly, this can be done without increasing reliance on fertilizers, which are linked to biodiversity loss and pollution.

Senior postdoctoral researcher at the Earlham Institute and co-first author Dr. Rachel Rusholme-Pilcher said, "We've revealed layers of hidden diversity spanning our modern wheat variations. This diversity is likely to underpin the success of wheat over such a wide range of global environments.

"We discovered how groups of genes work together as regulatory networks to control gene expression. Our research allowed us to look at how these network connections differ between wheat varieties revealing new sources of genetic diversity that could be critical in boosting the resilience of wheat."

Furthermore, this work has created an important resource for the worldwide wheat research community鈥攁 clear example of how national and international collaboration and new technologies can lead to scientific breakthroughs in global food security.

Much of the untapped genetic diversity may stem from how wheat has adapted to different environments over time, shaped by over 100 years of modern breeding and more than 10,000 years of cultivation.

Deputy group leader in the Plant Genome and Systems Biology Group at Helmholtz Munich Dr. Manuel Spannagl, said, "The new expression atlas allowed us to independently predict and compare the gene content of the wheat cultivars. We used those gene predictions together with the pan-transcriptome data to identify pronounced variation in the prolamin superfamily and immune-reactive proteins across cultivars."

Transcript isoform sequencing and de novo annotation was carried out by the Technical Genomics and Core Bioinformatics Groups at the Earlham Institute.

Dr. Karim Gharbi, head of Technical Genomics at the Earlham Institute, said, "This work demonstrates the power of technology to reveal novel biology, in this case hidden functional diversity which had not been documented before. Wheat pangenomics resources are growing rapidly with more diversity yet to be discovered."