Human noroviruses, GII.4 strains in particular, are the chief drivers of acute viral gastroenteritis around the world, a condition for which there are no vaccines or antivirals. Understanding how these viruses enter cells ...
Bioengineers at the University of California San Diego have developed a powerful new technology that can map the entire network of RNA-protein interactions inside human cells—an achievement that could offer new strategies ...
It's no secret that we need new ways to treat and detect disease, including cancer. Specifically, we need better biomarkers that can be used for diagnosis and better ways to selectively get medicine where we want it to go ...
Researchers at Integra Therapeutics, in collaboration with the Pompeu Fabra University (UPF) Department of Medicine and Life Sciences (MELIS) and the Center for Genomic Regulation (CRG), have designed and experimentally validated ...
Researchers from the National University of Singapore (NUS) have successfully applied cryo-electron microscopy (cryo-EM) to unveil the molecular structures of critical protein machines that transport lipids and maintain the ...
Egg whites may be perfect for a health-conscious breakfast, but egg yolks turned out to be the key ingredient for cultivating bird embryonic stem cells (ESCs) in the lab. Using a growing medium of egg yolk along with a few ...
Researchers at Baylor College of Medicine have developed a powerful new data analysis method named COOKIE-Pro (Covalent Occupancy Kinetic Enrichment via Proteomics) that provides a comprehensive, unbiased view of how a class ...
A new tool greatly improves scientists' ability to identify and study proteins that regulate gene activity in cells, according to research led by Weill Cornell Medicine investigators. The technology should enable and enhance ...
Cancer cells are pretty bold and clever—they hijack cellular survival and healing processes in order to fuel their growth, spread throughout the body, and ensure their own survival. The unfolded protein response, which ...
The yeast fungus Candida albicans not only uses the toxin candidalysin to cause infections, but also to colonize the oral mucosa inconspicuously—but only in finely balanced amounts. Too little toxin prevents oral colonization, ...
