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Biochemistry Aug 23, 2023

Research team leverages power of ribosomes to develop chemical libraries

A research team led by University of California, Irvine scientists has developed an innovative method for quickly and efficiently creating vast collections of chemical compounds used in drug discovery by harnessing the power ...

Biochemistry Aug 3, 2023

New, simple and accessible method creates potency-increasing structure in drugs

Chemical structures called cyclopropanes can increase the potency and fine-tune the properties of many drugs, but traditional methods to create this structure only work with certain molecules and require highly reactive—potentially ...

Molecular & Computational biology Aug 1, 2023

Researchers explore use of AI to improve COVID-19 drug design

Discovering and developing drugs can be slow, costly and high-risk, but harnessing advances in artificial intelligence (AI) can help with these processes, say Brock University researchers.

Biochemistry Jul 31, 2023

Researchers use quantum circuit to identify single nucleotides

DNA sequencing technology, i.e., determining the order of nucleotide bases in a DNA molecule, is central to personalized medicine and disease diagnostics, yet even the fastest technologies require hours, or days, to read ...

Biotechnology Jul 28, 2023

Researchers develop method to predict gene expression across different tissues and cell types

In recent years, a virtual tidal wave of studies linking the expression of certain genes to complex diseases as varied as cancer and diabetes has raised hopes for major advances in medical treatment and drug discovery.

Analytical Chemistry Jul 19, 2023

Scientists develop revolutionary new approach to designing catalysts for chemical reactions

Chemists at King's College London have made a breakthrough in the way they develop artificial helix shapes for the amino acids that constitute proteins. These new synthetic shapes have the potential to transform processes ...

Bio & Medicine Jul 17, 2023

Researchers craft 'origami DNA' to control virus assembly

Griffith University researchers have played a key role in using DNA "origami" templates to control the way viruses are assembled.

Biotechnology Jul 13, 2023

Researchers demonstrate the power of quantum computing in drug design

Gero, an AI-driven biotech focused on aging and longevity, has demonstrated the feasibility of applying quantum computing for drug design and generative chemistry, which now offers significant promise for the future of healthcare. ...

Biochemistry Jul 13, 2023

Catalyst's ability to mimic liver enzyme could broaden scope of pharmaceutical drug discovery

When a human consumes a pharmaceutical drug, enzymes in the liver break down the substance into metabolites that are water soluble, so the body can more easily excrete them. In some cases, the resulting metabolites may have ...

Cell & Microbiology Jul 7, 2023

Developing a human malaria-on-a-chip disease model

In a new report published on Scientific Reports, Michael J. Rupar, and a research team at Hesperos Inc., Florida, U.S., developed a functional, multi-organ, serum-free system to culture P. falciparum—a protozoan that predominantly ...

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